Lasers are becoming increasingly popular for numerous medical applications. The use of femtosecond laser pulses is particularly attractive for such applications thanks to the “cold” process of tissue ablation which is confined only to the focal volume of the laser beam. In our group we use femtosecond pulses of various wavelength to excite specifically targeted noble-metal nanoparticles at their plasmonic resonance. The combined effect of the short pulses and small particles allows for specific manipulations of cells and tissue with minimal toxicity and collateral damage.

Specific cell fusionSpecific cell fusion
The attachment between two different cells via a bispecific nanoparticle is illustrated in Figure 1a. Following the addition of the nanoparticles…
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Nano-manipulations of cellsNano-manipulations of cells
Specifically targeting and manipulating living cells is a key challenge in biomedicine and in cancer research in particular…
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Nanoparticle-pulse interactionNanoparticle-pulse interaction
Gold nanoparticles find a wide range of applications in optics and photonics; however, their detailed interaction with intense laser light is only partially understood…
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Nano-manipulations of macro-moleculesNano-manipulations of macro-molecules
The unique optical properties of gold nanoparticles make them attractive for a wide range of applications which require optical detection and manipulation techniques…
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